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Literature summary for 2.1.1.172 extracted from
- Discovery of a novel small molecular peptide that disrupts helix 34 of bacterial ribosomal RNA (2019), RSC Adv., 9, 40268-40276 .
No PubMed abstract available
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| KNHDWGV | 7-mer peptide that binds to the second strand of 16S h34 RNA. Binding of the peptide alters RNA structure and inhibits the binding of the ribosomal RNA small subunit methyltransferase C. The addition of the peptide also increases the lag phase of bacterial growth | Escherichia coli |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant protein | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RsmC | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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